Semax is a synthetic heptapeptide derived from adrenocorticotropic hormone (ACTH) fragment 4-10, with no hormonal activity. It has attracted growing interest in research focused on cognitive enhancement, neuroprotection, and cerebrovascular health.
Studies have shown that Semax increases levels of brain-derived neurotrophic factor (BDNF) and other neurotrophins, promoting neuronal survival and synaptic plasticity. It also influences serotonin and dopamine metabolism, improving attention, learning, and memory. It may also play a role in stroke recovery, neuroinflammation reduction, and protection against oxidative stress-induced neuronal damage.
BDNF upregulation and neuroplasticity enhancement
Cognitive improvement and memory consolidation
Cerebrovascular circulation and stroke recovery
Neuroprotection and oxidative stress reduction
Attention deficit and age-related cognitive decline research