Home Special MOTS-c

MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-c) is a 16-amino-acid peptide encoded by mitochondrial DNA. It has attracted growing interest in research focused on metabolic health, cellular protection, and aging.

Studies have shown that MOTS-c activates AMPK pathways, improves glucose uptake, enhances insulin sensitivity, and promotes lipid oxidation. It may also play a role in mitochondrial function, inflammation control, and resistance to oxidative stress.

Key Research Areas:

  • AMPK activation and metabolic regulation

  • Insulin sensitivity and glucose metabolism

  • Cellular resilience to oxidative stress

  • Mitochondrial protection and longevity studies

  • Anti-inflammatory and neuroprotective pathways

Anti-agingFor research use onlyMetabolic healthMitochondrial health