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Melanotan II

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Melanotan II (also known as Melanotan-2 or MT-2) is a synthetic analogue of alpha-melanocyte-stimulating hormone (α-MSH) with non-selective melanocortin receptor activity. It has attracted growing interest in research focused on skin pigmentation, sexual function, and appetite regulation.

Studies have shown that Melanotan II activates melanocortin receptors (MC1R, MC3R, MC4R, and MC5R), stimulating eumelanin production for UV-independent tanning, while also influencing erectile function and satiety pathways. It may also play a role in libido enhancement, neuroprotection, and modulation of inflammatory responses.

Key Research Areas:

  • MC1R activation and photoprotective tanning

  • MC4R-mediated appetite suppression and weight regulation

  • Erectile dysfunction and sexual health research

  • Neuroprotective and anti-inflammatory pathways

  • Erythropoietic protoporphyria (EPP) studies

Appetite controlFor research use onlySexual healthTanning