IGF-1LR3
Contact Us →IGF-1 LR3 (Insulin-like Growth Factor-1 Long Arginine 3) is a synthetic analogue of human IGF-1 with an arginine substitution at position 3 and a 13-amino acid extension peptide. It has attracted growing interest in research focused on muscle growth, tissue repair, and metabolic health.
Studies have shown that IGF-1 LR3 exhibits significantly reduced binding to IGF-binding proteins (IGFBPs), resulting in a longer half-life and enhanced bioavailability compared to native IGF-1. It activates the IGF-1 receptor, promoting protein synthesis, cell proliferation, and glucose uptake. It may also play a role in muscle wasting prevention, neuroprotection, wound healing, and recovery from injury.
Key Research Areas:
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IGF-1 receptor activation and anabolic signaling
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Muscle hypertrophy and protein synthesis promotion
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Reduced IGFBP binding and prolonged bioactivity
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Glucose metabolism and insulin sensitization
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Neuroprotection and tissue regeneration research
