CJC-1295 (with DAC) is a synthetic analogue of growth hormone-releasing hormone (GHRH) modified with a drug affinity complex (DAC) that binds covalently to serum albumin, significantly extending its half-life. It has attracted growing interest in research focused on sustained growth hormone release, metabolic health, and anti-aging.
Studies have shown that CJC-1295 (with DAC) stimulates endogenous growth hormone secretion from the pituitary gland by binding to GHRH receptors, leading to prolonged elevation of growth hormone and insulin-like growth factor-1 (IGF-1) levels for up to 7-10 days. It promotes protein synthesis, lipolysis, and tissue repair. It may also play a role in muscle mass preservation, fat metabolism enhancement, sleep improvement, and recovery from age-related decline.
GHRH receptor activation and sustained GH release
Prolonged IGF-1 elevation and metabolic modulation
Muscle mass preservation and protein synthesis
Lipolysis and long-term fat metabolism
Anti-aging and age-related hormone decline research